Dynorfin

Dinorfin (Dyn) je opioidní peptid, který vzniká z prekurzoru prodynorfinu působením proproteinu kovertáza 2 (PC2) ve formě dynorfinu A, dynorfinu B a α/β-neo-endorfinu.[1]

Dynorfin objevil v polovině 70. let 20. století Avram Goldstein.[2]

Odkazy

Reference

V tomto článku byl použit překlad textu z článku Dynorphin na anglické Wikipedii.

Day R, Lazure C, Basak A, Boudreault A, Limperis P, Dong W, Lindberg I. Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity. J. Biol. Chem.. January 1998, s. 829–36. DOI 10.1074/jbc.273.2.829. PMID 9422738. (anglicky)
A. Goldstein u. a.: Dynorphin-(1-13), an extraordinarily potent opioid peptide. In: Proc Natl Acad Sci, 76/1979, S. 6666–70. PMID 230519.

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[pmid9422738-1] Day R, Lazure C, Basak A, Boudreault A, Limperis P, Dong W, Lindberg I. Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity. J. Biol. Chem.. January 1998, s. 829–36. DOI 10.1074/jbc.273.2.829. PMID 9422738. (anglicky)

[2] A. Goldstein u. a.: Dynorphin-(1-13), an extraordinarily potent opioid peptide. In: Proc Natl Acad Sci, 76/1979, S. 6666–70. PMID 230519.